Best Hotels in South Carolina

Below is the list of Best Hotels in South Carolina. The number one hotel is Holiday Inn Hotel Historic District in Charleston. The next few hotels in the top 5 are French Quarter Inn in Charleston, Harbour View Inn in Charleston, Marriott Myrtle Beach Resort and Spa at Grande Dunes in Myrtle Beach and Hampton Inn & Suites Myrtle Beach/Oceanfront in Myrtle Beach. Worth mentioning are Staybridge Suites Myrtle Beach, Myrtlewood Villas, and 3 others. For more hotels in South Carolina see the city links below including Charleston, Columbia, Myrtle Beach, Greenville and Moncks Corner.

Top 10 Hotels in South Carolina

1. Holiday Inn Hotel Historic District
   125 Calhoun St, Charleston, SC 29401  • 843-805-7900
   
   • 487 Reviews • 11 Sources

   
   
2. French Quarter Inn
   166 Church St., Charleston, SC, 29401  • 843-722-1900
   
   • 271 Reviews • 13 Sources

   
   
3. Harbour View Inn
   2 Vendue Range, Charleston, SC 29401  • 843-853-8439
   
   • 205 Reviews • 10 Sources

   
   
4. Marriott Myrtle Beach Resort and Spa at Grande Dunes
   8400 Costa Verde Drive, Myrtle Beach, SC 29572  • 843-449-8880
   
   • 190 Reviews • 6 Sources

   
   
5. Hampton Inn & Suites Myrtle Beach/Oceanfront
   1803 South Ocean Blvd, Myrtle Beach, SC 29577  • 877-946-6400
   
   • 186 Reviews • 5 Sources

   
   
6. Shem Creek Inn
   1401 Shrimp Boat Lane, Mount Pleasant, SC 29464  • 800-523-4951
   
   • 107 Reviews • 11 Sources

   
   
7. Disney Hilton Head Isl Rst
   22 Harbourside Lane, Hilton Head Island, SC 29928  • 407-939-7540
   
   • 101 Reviews • 9 Sources

   
   
8. Wentworth Mansion
   149 Wentworth St, Charleston, Sc 29401  • 843-8531886
   
   • 80 Reviews • 11 Sources

   
   
9. Main Street Inn
   2200 Main St, Hilton Head Island, SC 29926  • 843-681-3001
   
   • 74 Reviews • 8 Sources

   
   
10. Hilton Greenville
    45 West Orchard Park Drive, Greenville, SC 29615  • 800-4458667
    
    • 66 Reviews • 9 Sources

    
    

Honorable Mentions for Hotels in South Carolina

• Staybridge Suites Myrtle Beach
  3163 Outlet Blvd, Myrtle Beach, SC 29579  • 843-903-4000
  


• Myrtlewood Villas
  1410 48TH Ave N Exit, Myrtle Beach, SC 29577  • 888-297-6200
  


• Market Street Inn
  48 N Market St, Charleston, SC 29401  • 843-723-2177
  


• Spartanburg Marriott Renaissance Park
  299 N Church St, Spartanburg, SC 29306  • 800-327-6465
  


• Abingdon Manor - Country Inn & Restaurant
  307 Church St, Latta, SC 29565  • 843-752-5090